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This review shows that smoking, like the Western diet (Kopp, 2019), causes a significant distortion of physiological balance, characterized by dysregulation of the SNS, the RAAS and the immune system, as well as disruption of physiological insulin and oxidant/antioxidant homeostasis, manifested as OxS and insulin resistance

In 1964, the Surgeon General seemed to put an end to any controversy when he released the report of an independent advisory committee that had considered more than 7,000 published articles

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